Help: When things are bad.
Thanks: When things are good.
Wow: When the abundance of beauty in the world overwhelms her.
Ms. Lamott writes headlong and breathless throughout the book's 102 pages and her words can make you laugh and cry at the same time. This is not the first book that takes the reader along with her as she creates a spiritual life for herself. Others include Traveling Mercies, Plan B, and Grace (Eventually).
You can read Help, Thanks, Wow in an hour. Then go forth, read Bird by Bird (her book on writing), and live your life with an appreciation of the good, the bad, and the beautiful.